Acquired von Willebrand Syndrome and Platelet Function Defects during Extracorporeal Life Support (Mechanical Circulatory Support)
نویسندگان
چکیده
منابع مشابه
Acquired von Willebrand syndrome in cardiogenic shock patients on mechanical circulatory microaxial pump support
Early use of mechanical circulatory support, e.g. veno-arterial extracorporeal membrane oxygenation (ECMO) or left ventricular unloading by microaxial pump in refractory cardiogenic shock is recommended in current guidelines. Development of acquired von Willebrand Syndrome (AVWS) in patients with left ventricular assist devices (LVADs) and ECMO has been reported. There is an increasing number o...
متن کاملPlatelet Secretion Defects and Acquired von Willebrand Syndrome in Patients With Ventricular Assist Devices
BACKGROUND The number of implanted ventricular assist devices (VADs) has increased significantly recently. Bleeding, the most frequent complication, cannot be solely attributed to anticoagulation therapy. Acquired von Willebrand syndrome (AVWS) caused by increased shear stress is frequent in VAD patients and can increase the bleeding risk. The HeartMate III (HM III) is a novel left VAD featurin...
متن کاملMechanical Circulatory Support
The role of mechanical circulatory device therapy has progressed rapidly over the last 2 decades, from supporting the failing heart in hospitalized patients awaiting heart transplantation to permanent or “destination” outpatient therapy in individuals with end-stage systolic heart failure (HF) for whom transplantation is not an option. Over this period, devices themselves have evolved through s...
متن کاملPediatric Mechanical Circulatory Support
Mechanical circulatory support (MCS) in the pediatric heart failure population has a limited history especially for infants, and neonates. It has been increasingly recognized that there is a rapidly expanding population of children diagnosed and living with heart failure. This expanding population has resulted in increasing numbers of children with medically resistant end-stage heart failure. T...
متن کاملMyocardial oxidative metabolism and protein synthesis during mechanical circulatory support by extracorporeal membrane oxygenation.
Extracorporeal membrane oxygenation (ECMO) provides essential mechanical circulatory support necessary for survival in infants and children with acute cardiac decompensation. However, ECMO also causes metabolic disturbances, which contribute to total body wasting and protein loss. Cardiac stunning can also occur, which prevents ECMO weaning, and contributes to high mortality. The heart may spec...
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ژورنال
عنوان ژورنال: Hämostaseologie
سال: 2020
ISSN: 0720-9355,2567-5761
DOI: 10.1055/a-1150-2016